Unscheduled vaginal bleeding and associated gynecologic care in postmenopausal women using hormone replacement therapy: comparison of cyclic versus continuous combined regimen.
- Author:
Mi Jung LEE
;
Jeong A NA
;
In Ho KIM
;
Jun Young HUR
;
Yong Kyun PARK
;
Kap Soon JU
;
Ho Suk SAW
;
Soo Yong CHOUGH
- Publication Type:Original Article
- Keywords:
hormone replacement therapy;
unscheduled vaginal bleeding;
gynecologic procedures
- MeSH:
Ambulatory Care;
Biopsy;
Female;
Follow-Up Studies;
Hemorrhage;
Hormone Replacement Therapy*;
Humans;
Uterine Hemorrhage*
- From:Korean Journal of Obstetrics and Gynecology
2000;43(2):216-220
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: To measure gynecologic resources required to care for women who have unscheduled vaginal bleeding while using hormone replacement therapy. MATERIALS AND METHODS: Between January 1996 to December 1998, women presenting with abnormal withdrawal bleeding on HRT were identified and associated clinic visits and gynecologic procedures were recorded during a mean follow-up of 2 years. RESULTS: Among women using cyclic HRT, 28.9% had> OR =1 visit for unscheduled vaginal bleeding 8.7% had> OR =1 endometrial biopsy. Among women using continuous combined HRT, 19.3% had> OR =1 visit for unscheduled vaginal bleeding and 6.4% had> OR =1 endometrial biopsy. The gynecologic procedures used in women using cyclic HRT were 20% of reassurance, 50% of ultrasonograpy, 30% of endometrial biopsy and in women using continuous combined HRT were 50% of reassurance, 16.6% of ultrasonograpy, 33.3% of endometrial biopsy. The results of endometrial biopsy were reported all the benign condition. CONCLUSION(S): Unscheduled vaginal bleeding markedly decreased after 12 months of therapy in women using continuous combined HRT but did not decline among those using cyclic HRT.
