Molecular biology for myelodysplastic syndrome: An update
10.3781/j.issn.1000-7431.2012.02.012
- Author:
Jing LUO
1
Author Information
1. Department of Hematology
- Publication Type:Journal Article
- Keywords:
Hematologic neoplasms;
Myelodysplastic-myeloproliferative diseases;
Tumor markers biological
- From:
Tumor
2012;32(2):137-141
- CountryChina
- Language:Chinese
-
Abstract:
The pathogenesis of myelodysplastic syndrome (MDS) has not been fully clarified, it may be closely associated with the great heterogeneity in biology that characterizes this group of diseases. Recent studies have revealed that some changes in molecular biology, including abnormal expression of disease gene, abnormal epigenetics, and abnormalities of hematopoietic stem cells, were closely correlated with the pathogenesis of MDS. This article reviews the newly discovered changes of molecular and biological characteristics associated with the development of MDS. Copyright © 2012 by TUMOR.
