The role of acid sphingomyelinase in the development and progression of tumors and its application value
10.3781/j.issn.1000-7431.2012.07.016
- Author:
Bai-Hong ZHANG
1
Author Information
1. Department of Oncology
- Publication Type:Journal Article
- Keywords:
Acid sphingomyelinase;
Neoplasms;
Tumorigenesis
- From:
Tumor
2012;32(7):564-566
- CountryChina
- Language:Chinese
-
Abstract:
Acid sphingomyelinase (aSMase) is an important enzyme in sphingolipid metabolism. Studies concerning the relationship between aSMase and tumor are relatively rare. However, the relationship between aSMase and the development and progression of tumors has already been demonstrated in previously published research. In this review, the mechanism of aSMase activation and the role of aSMase in the development and progression of tumors as well as its application value are summarized. Copyright © 2012 by TUMOR.