Comparison of enhancement features of peripheral intrahepatic cholangiocarcinoma on contrastenhanced ultrasound and dynamic enhanced MRI
10.3781/j.issn.1000-7431.2014.33.459
- Author:
Feng MAO
1
Author Information
1. Department of Ultrasound, Zhongshan Hospital, Fudan University
- Publication Type:Journal Article
- Keywords:
Contrast-enhanced ultrasound;
Diagnosis;
Intrahepatic cholangiocarcinoma;
Magnetic resonance imaging
- From:
Tumor
2014;34(11):1023-1027
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To analyze and compare the imaging characteristics of contrast-enhanced ultrasound (CEUS) and dynamic enhanced magnetic resonance imaging (MRI) for diagnosis of peripheral intrahepatic cholangiocarcinoma, aiming to increase the accuracy of diagnostic imaging. Methods: The imaging characteristics of CEUS and dynamic enhanced MRI in 51patients with peripheral intrahepatic cholangiocarcinoma confirmed by surgical pathology or fine needle aspiration biopsy were retrospectively analyzed and compared. Results: Fifty-five lesions in fifty-one cases were analyzed. On CEUS, the hyperenhancement in arterial phase was seen in all 55 lesions, iso-echo in 8 lesions and hypo-echo in 47 lesions in portal phase, and hypo-echo in all 55 lesions in delayed phase. On enhanced MRI, all 55 lesions displayed the same characteristics as CEUS in arterial phase except 44 lesions continuously displaying hyper-intensity and 11lesions displaying hypo-intensity in portal and delayed phases. On CEUS, 42 (76.4%) lesions displayed rim-like enhancement, and 13 (23.6%) lesions displayed gross enhancement. During the process of enhancement, the pattern of branch-like extending inwardly was observed in 40 (72.7%) lesions. On dynamic enhanced MRI, 40 (72.7%) lesions showed the pattern of rimlike enhancement, and other 15 (27.3%) lesions showed gross enhancement. The features of CEUS were rim-like enhancement in arterial phase with branch-like extending inwardly. A large proportion of the lesions displayed heterogeneous enhancement when reaching the peak intensity. The characteristics of dynamic enhanced MRI were similar to CEUS in arterial phase, but a continuous enhancement was seen in portal and delayed phases, indicating enhancement in late phase. The occurrence rate of characteristic manifestation on CEUS was 70.9% (39/55) according to the standard of "fast-in and fast-out" and "rimlike" and/or "branch-like" enhancement. The occurrence rate of characteristic manifestation on dynamic enhanced MRI was 69.1% (38/55) according to the standard of "rim-like enhancement" in arterial phase and "delayed enhancement" in late phase. There was no difference in the occurrence rate of characteristic manifestation between CEUS and dynamic enhanced MRI (P = 1.000). Conclusion: The characteristic manifestations on CEUS and dynamic enhanced MRI for the diagnosis of peripheral intrahepatic cholangiocarcinoma display a high diagnostic value.
