Advances in long non-coding RNA in prostate cancer
10.3781/j.issn.1000-7431.2014.02.015
- Author:
Xiao-Jun LIU
1
Author Information
1. Department of Urology
- Publication Type:Journal Article
- Keywords:
Gene expression;
Heredity;
Long non-coding RNAs;
Prostatic neoplasms
- From:
Tumor
2014;34(2):187-190
- CountryChina
- Language:Chinese
-
Abstract:
Long non-coding RNAs (lncRNAs) are RNA transcripts longer than 200 nt without any protein coding ability. LncRNAs perform biological functions through a variety of mechanisms. They have a close association with human tumors, regulating the expression of genes at the epigenetic, transcriptional and post-transcriptional levels. LncRNAs are wildly involved in biological and pathological process and play a significant role in the development of cancer. This article reviews the research in the current status of lncRNAs in prostate cancer. Copyright © 2014 by TUMOR.