Clinical features and treatment of intracranial hemangiopericytoma
10.3781/j.issn.1000-7431.2014.03.013
- Author:
Ying-Zi LIU
1
Author Information
1. Department of Neurosurgery, Fourth Hospital of Hebei Medical University, Tumor Hospital of Hebei Province
- Publication Type:Journal Article
- Keywords:
Central nervous system neoplasms;
Hemangiopericytoma;
Progression-free survival;
Radiotherapy;
Surgical procedures, operative
- From:
Tumor
2014;34(3):275-280
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To discuss the clinical features and treatment of intracranial hemangiopericytoma (HPC). Methods: The medical records including clinical features, imaging features, pathological results and treatment methods in 31 patients with HPC were reviewed retrospectively. To compare the difference in progression-free survival (PFS) among patients receiving different treatments. Results: Thirty-one patients with initial HPC were treated with operation and radiation. Gross total removal (GTR) was achieved in 16 patients, followed by postoperative adjuvant fractionated external beam radiation therapy (EBRT). Of 15 patients with subtotal removal (STR), 6 patients accepted EBRT, and 9 patients were treated with adjuvant gamma knife surgery (GKS). The median PFS of patients with GTR (89 months, 64-126 months) was longer than that of patients with STR (49 months, 26-81 months) (P < 0.01). However, there was no significant difference in the median PFS of patients with STR between undergoing EBRT (49 months, 26-81 months) and GKS (47 months, 29-78 months) (P > 0.05). Conclusion: GTR followed by adjuvant radiation provides patients with a better outcome. Copyright © 2014 by TUMOR.
