Progress in influence of inflammatory microenvironment mediated by tumor-associated macrophages on liver cancer stem cells
10.3781/j.issn.1000-7431.2017.55.192
- Author:
Yongxu CHEN
1
Author Information
1. School of Medicine, South China University of Technology
- Publication Type:Journal Article
- Keywords:
Liver neoplasms;
Macrophages;
Neoplastic stem cells;
Tumor microenvironment
- From:
Tumor
2017;37(9):989-994
- CountryChina
- Language:Chinese
-
Abstract:
The development of liver cancer is associated with the inflammation caused by hepatitis virus. Macrophages are one of the most important cells in chronic inflammation response. The activated M2-type macrophages can secrete a series of inflammatory factors to participate in the regulation of inflammatory microenvironment, and lead to the formation of liver cancer stem cells. In this review, the relationship between tumor-associated macrophages and cancer stem cells is discussed, in order to provide a new idea for the prevention and treatment of tumor.
