Reliability and validity of EQ-5D-3L and FACT in Beijing's patients with cancer and precancerosis
10.3781/j.issn.1000-7431.2017.22.242
- Author:
Hanyue DING
1
Author Information
1. Department of Public Health Information Research, Institute of Medical Information, Chinese Academy of Medical Sciences
- Publication Type:Journal Article
- Keywords:
Euro-Qol-5 Dimensions;
Functional Assessment of Cancer Therapy;
Neoplasms;
Quality of life;
Reliability;
Validity
- From:
Tumor
2017;37(9):953-959
- CountryChina
- Language:Chinese
-
Abstract:
Objective: Based on the Cancer Screening Program in urban districts in Beijing from 2013 to 2014, target populations included pulmonary, mammary, esophageal, colorectal, hepatic and gastric cancers and precancerosis patients. The EQ-5D-3L and Functional Assessment of Cancer Therapy (FACT) questionnaires were used to measure the patients' quality of life and the reliability and validity of EQ-5D-3L and FACT were analyzed. Methods: The EQ-5D-3L and FACT questionnaires were used to measure 1 001 patients with cancer and precancerosis. The Cronbach's α coefficient was calculated to test the consistent reliability of EQ-5D-3L and FACT. The factor analysis was used to measure the construct validity of FACT and the FACT as standard to test the convergent validity of EQ-5D-3L. Results: Cronbach's α coefficients of EQ-5D-3L for pulmonary, breast, esophageal, colorectal, hepatic and gastric cancers were 0.846, 0.805, 0.877, 0.862, 0.793 and 0.844, respectively; the Cronbach's α coefficients of FACT were 0.935, 0.916, 0.950, 0.952, 0.915 and 0.953, respectively. The cumulative explained variances of FACT were 64.28%, 65.15%, 71.43%, 67.21%, 64.76% and 70.56%, respectively. Compared with FACT, the convergent validities of EQ-5D-3L were 0.592, 0.503, 0.715, 0.672, 0.561 and 0.444, respectively. The convergent validities of EQ-Visual Analogue Scale (VAS) were 0.553, 0.606, 0.576, 0.579, 0.361 and 0.364, respectively. Conclusion: EQ-5D-3L and FACT questionnaires for pulmonary, breast, esophageal, colorectal, hepatic and gastric cancers and the precancerosis patients are verified to have good reliabilities, and the FACT questionnaires of six types of cancers are being verified to have good construct validities. The EQ-5D-3L questionnaires for esophageal, colorectal, pulmonary, hepatic and breast cancers are being verified to have good convergent validities; but for the gastric cancer and precancerosis, there are limited validities.
