Detection of circulating tumor DNAs and its application in breast cancer
10.3781/j.issn.1000-7431.2018.55.486
- Author:
Yanhui ZHU
1
Author Information
1. Department of Breast, Nanfang Hospital, Southern Medical University
- Publication Type:Journal Article
- Keywords:
Breast neoplasms;
Circulating;
Diagnosis;
Neoplastic cells;
Prognosis;
Tumor burden
- From:
Tumor
2018;38(1):73-77
- CountryChina
- Language:Chinese
-
Abstract:
With the development of detection technology, circulating tumor DNAs have broad application prospects in early diagnosis, prognosis evaluation and curative effect and tumor load monitoring. The application of circulating tumor DNAs in breast cancer has also become a hotspot in recent years, especially in the early diagnosis of breast cancer, tumor burden and drug resistance. At the same time, chemotherapy, targeted therapy, and endocrine therapy for breast cancer will be more individualized and targeted. The existing imaging and clinical tests provide limited individualized information for comprehensive treatment of breast cancer. The advantage of circulating tumor DNA detection is likely to change the existing treatment strategies of breast cancer and provide more precise treatment for patients.