Basic science related to tendinopathy: Microbiomechanics and stress shielding
10.3969/j.issn.2095-4344.2436
- Author:
Chunyu LIU
1
Author Information
1. Beijing Sport University
- Publication Type:Journal Article
- Keywords:
Biomechanics;
Enthesis;
Extracellular matrix;
Injury;
Microstructure;
Stress shielding;
Tendinopathy;
Tidemark
- From:
Chinese Journal of Tissue Engineering Research
2020;24(5):766-772
- CountryChina
- Language:Chinese
-
Abstract:
BACKGROUND: Tendon is a special connective tissue that can transmit the force generated by the muscle to the bone through the enthesis. The occurrence of tendinopathy is closely related to the mechanical characteristics of tendon and enthesis and its micro-structure, but the specific mechanism still remains controversial OBJECTIVE: To summarize the micro-structure of tendon and en thesis, the biomechanical characteristics of tendon, the healing and repair of tendon injuries, and the biomechanical factors related to chronic tendinopathy. METHODS: CNKI, VIP, CBM, WanFang, PubMed and Embase databases were searched. The articles concerning micro-structure of tendon and enthesis, relationship between tendinopathy/enthesis and stress, and biomechanical mechanisms of tendinopathy/enthesis were selected. RESULTS AND CONCLUSION: The biomechanical properties of tendon and enthesis are closely related to their microstructures. The biomechanical properties of tendon are reduced due to the damage of their microstructures in the process of repair. The occurrence and development of chronic tendinopathy are related to the microstructures and biomechanical characteristics of enthesis. Compression load and stress shielding of enthesis may play a key role, but further high-quality studies on the specific mechanism are still required.
