Late-Developing Metastatic Malignant Melanoma in the Thoracic Spine Originating from Choroidal Melanoma.
10.14245/kjs.2017.14.2.53
- Author:
Jun Kyu HWANG
1
;
Kyung Hyun KIM
;
Ji Sup KIM
;
Sung Jun AHN
;
Sung Uk KUH
Author Information
1. Department of Neurosurgery, Gangnam Severance Hospital, Spine and Spinal Cord Institute, Yonsei University College of Medicine, Seoul, Korea. kuhsu@yuhs.ac
- Publication Type:Case Report
- Keywords:
Choroidal tumor;
Malignant melanoma;
Spine metastasis
- MeSH:
Choroid*;
Drug Therapy;
Electrons;
Female;
Flank Pain;
Humans;
Magnetic Resonance Imaging;
Melanoma*;
Middle Aged;
Neoplasm Metastasis;
Pathology;
Radiotherapy;
Spine*
- From:Korean Journal of Spine
2017;14(2):53-56
- CountryRepublic of Korea
- Language:English
-
Abstract:
A 54-year-old woman visited Gangnam Severance Hospital for left side flank pain. She had a history of total removal of malignant melanoma on the left eye ball 20 years prior. No evaluation had been performed since then. A paravertebral mass at thoracic ninth level (T9) was discovered on spinal magnetic resonance imaging, and pathology confirmed malignant melanoma. Following positron emission tomography-computed tomography, no other metastasis was discovered. After removal of the paravertebral mass, palliative chemotherapy (dacabarzine + tamoxifene) was administered in 3 cycles over 2 months. Radiotherapy with simultaneous integrated boost technique was performed at 4,350 cGy total over 15 days, 290 cGy per delivery, and was administered with the first cycle of palliative chemotherapy. Despite this treatment, multiple metastases developed throughout her body 7 months later, and the patient is continuing chemotherapy.
