Research advances on alkaloids against tuberculosis
10.7501/j.issn.0253-2670.2020.03.033
- Author:
Ya-Ling CHEN
1
Author Information
1. Chongqing Public Health Medical Center
- Publication Type:Journal Article
- Keywords:
Alkaloids;
Diversity;
Mechanism;
Mycobacterium tuberculosis;
Tuberculosis
- From:
Chinese Traditional and Herbal Drugs
2020;51(3):799-805
- CountryChina
- Language:Chinese
-
Abstract:
Tuberculosis is one of the diseases with high incidence and mortality in the world. In the face of the increasing severe challenges of tuberculosis, there is a key to fight against tuberculosis by finding new ways and new ideas to develop new anti-tuberculosis drugs. Alkaloid compounds are widely distributed in natural medicines, which have the characteristics of biodiversity, chemical structure diversity and biological activity diversity, and most alkaloids have anti-tuberculosis activity. This article reviews the research progress of the effects of alkaloids on tuberculosis and the mechanism of anti-tuberculosis in recent years, which may summarize the characteristics of different types of alkaloids against tuberculosis and provide reference for further research, development and utilization of these compounds against tuberculosis.
