Chemical constituents of Artemisia rupestris
10.7501/j.issn.0253-2670.2020.13.005
- VernacularTitle: 新疆一枝蒿的化学成分研究
- Author:
Shao-Li XIA
1
Author Information
1. Key Laboratory of Xin'an Medicine, Ministry of Education, Anhui University of Chinese Medicine
- Publication Type:Journal Article
- Keywords:
7-methoxycoumarin;
Artemisia rupestris L.;
Imperatorin;
Oroxylin A;
Phellopterin;
Polyacetylenes
- From:
Chinese Traditional and Herbal Drugs
2020;51(13):3393-3398
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the chemical constituents of the whole plants of Artemisia rupestris. Methods: The chemical constituents were isolated and purified by silica gel, Sephadex LH-20 column chromatography and semi-preparative HPLC. The structures of the isolated compounds were identified by NMR and MS spectroscopic method. Results: Eighteen compounds were isolated and purified, which structures were identified as 2α-(2',4'-hexadiynoyl)-1,6-dioxaspiro [4,5]-deca-3-ene (1), chrysophanol (2), ethyl vanillate (3), methyl linolenate (4), 8,11-octadecadienoic acid methyl ester (5), eicosane coumaric acid ester (6), emodin (7), 2,5-di-tert-butylphenol (8), phellopterin (9), syringic acid (10), 7-methoxycoumarin (11), vanillin (12), imperatorin (13), oroxylin A (14), 5-hydroxy-3,4',6,7-tetramethoxyflavone (15), erucylamide (16), octadecyl 3-(3,5-di-tert-butyl-4-hydroxyphenyl) propanoate (17) and 3,5,3',4'-tetrahydroxy-6,7-dimethoxyflavone (18). Conclusion: Compounds 1, 4, 11-14 and 18 are isolated from A. rupestris for the first time, and all the other compounds were isolated from the genus Artemisia for the first time.
