Analysis of chemical differences between Cordyceps hawkesii and Cordyceps sinensis based on multivariate statistics
10.7501/j.issn.0253-2670.2020.16.028
- VernacularTitle: 基于多元统计学方法的亚香棒虫草与冬虫夏草化学差异研究
- Author:
Hong-Chun PAN
1
Author Information
1. Chongqing Traditional Herbal Pieces of Decoction Factory Co., Ltd.
- Publication Type:Journal Article
- Keywords:
Cordyceps hawkesii Gray;
Cordyceps sinensis;
Different components;
OPLS-DA;
UPLC-Q-TOF-MS
- From:
Chinese Traditional and Herbal Drugs
2020;51(16):4316-4324
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To analyze and identify the significant different components between Cordyceps hawkesii and Cordyceps sinensis by using method of ultra performance liquid chromatography quadrupole time of flight mass spectrometry (UPLC-Q-TOF-MS). Methods: Mass spectrometry combined with formula finder of PeakView software and database (Human Metabolome Database, Pub Chem, Metlin) and secondary fragmentation analysis, significant different components were identified and analyzed. Results: Through OPLS-DA analysis, it was found that 12 significant different components were identified. Eleven of them were amino acids and their metabolites, and one was phosphatidylcholine. Conclusion: Surprisingly, characteristic components such as cordycepin and adenosine were not identified by significant difference analysis. In this study, it was proved that C. hawkesii can be used as a supplementary resource instead of C. sinensis, which provided scientific support for the further development and utilization of C. hawkesii.
