Two new α-pyronoids from endophytic fungus Aspergillus oryzae derived from Paris polyphylla var. yunnanensis
10.7501/j.issn.0253-2670.2020.19.006
- VernacularTitle: 滇重楼内生真菌米曲霉中2个新的α-吡喃酮类化合物
- Author:
Hong-Mei YU
1
Author Information
1. School of Chemistry and Environment, Yunnan Minzu University
- Publication Type:Journal Article
- Keywords:
Asper-α-pyranone A;
Asper-α-pyranone B;
Aspergillus oryzae (Ahlb.) Cohn;
Endophytic fungi;
Paris polyphylla Smith var. yunnanensis (Franch.) Hand. -Mazz.;
Secondary metabolites;
Α-pyronoids
- From:
Chinese Traditional and Herbal Drugs
2020;51(19):4891-4895
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the chemical composition and structure of the secondary metabolites of the endophytic fungus Aspergillus oryzae from Paris polyphylla var. yunnanensis. Methods: A. oryzae was fermented by liquid fermentation. After extraction, it was separated and purified by various chromatography methods. The structure of the compounds was identified according to the physical and chemical properties and spectral data. Results: Four compounds were isolated and their structures were identified as 4-hydroxy-6-[(2S,3S)-3-hydroxybutan-2-yl]-3-methyl-2H-pyran-2-one (1), (R)-4-hydroxy-6-(1-hydroxy-2- methylpropyl)-3- methyl-2H-pyran-2-one (2), flufuran (3) and flufuran methyl ester (4). Conclusion: Compounds 1 and 2 are new α-pyronoids named asper-α-pyranone A and asper-α-pyranone B.
