Research progress on pharmacology effects and new drug delivery system of icaritin
10.7501/j.issn.0253-2670.2020.20.031
- VernacularTitle: 淫羊藿素药理作用及其新型给药系统的研究进展
- Author:
Hua-Ting ZENG
1
Author Information
1. Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Antitumor;
Icaritin;
New drug delivery system;
Pharmacology effects;
Research progress
- From:
Chinese Traditional and Herbal Drugs
2020;51(20):5372-5380
- CountryChina
- Language:Chinese
-
Abstract:
Icaritin is one of the major bioactive compounds of Epimedii Folium. In recent years, scientific and pharmacological studies have shown that icaritin possesses broad therapeutic effects, especially in anti-tumor, enhancing osteoprotective, cardioprotective, neuro-protective function. However, its clinical application was limited by poor water solubility, poor oral absorption and low bioavailability. New drug delivery system has great application prospect in improving solubility of icaritin, oral absorption and bioavailability. Therefore, the current review paper aims to summarize the pharmacological effects of icaritin and briefly introduce some new drug delivery of icaritin, to provide theoretical basis for its clinical application and new drug development.
