Ocular Dipping in Creutzfeldt-Jakob Disease.
10.3988/jcn.2014.10.2.162
- Author:
Fernando SIERRA-HIDALGO
1
;
Sara LLAMAS
;
Juan Francisco GONZALO
;
Carmen SANCHEZ SANCHEZ
Author Information
1. Department of Neurology, Hospital Universitario 12 de Octubre, Madrid, Spain. fsierra.hdoc@salud.madrid.org
- Publication Type:Case Report
- Keywords:
Creutzfeldt-Jakob disease;
ocular dipping;
coma;
occular bobbing
- MeSH:
Aged;
Brain;
Brain Stem;
Coma;
Creutzfeldt-Jakob Syndrome*;
Diagnosis;
Dyskinesias;
Eye Movements;
Female;
Humans;
Hypoxia-Ischemia, Brain;
Memory
- From:Journal of Clinical Neurology
2014;10(2):162-165
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: Ocular dipping (OD), or inverse ocular bobbing, consists of slow, spontaneous downward eye movements with rapid return to the primary position. It has been mainly reported following hypoxic-ischemic encephalopathy, but has also been described in association with other types of diffuse or multifocal encephalopathies and structural brainstem damage. CASE REPORT: We report the case of a previously asymptomatic 66-year-old woman who presented with confusion, recent memory disturbances, and abnormal involuntary movements, followed by a coma. Abnormal spontaneous vertical eye movements consistent with OD developed from the fourth day after admission, and the patient died 20 days later. The pathological examination of the brain confirmed the diagnosis of Creutzfeldt-Jakob disease. CONCLUSIONS: The precise location of damage causing OD is unknown. In contrast to ocular bobbing, OD has no localizing value itself, but structural brainstem damage is likely when it appears combined with other spontaneous vertical eye movements.
