Effect of Yaotongning Capsules combined with Imrecoxib Tablets in 60 cases of ankylosing spondylitis with cold-dampness and blood-stasis syndrome
10.7501/j.issn.0253-2670.2020.21.004
- VernacularTitle: 腰痛宁胶囊联合艾瑞昔布片治疗强直性脊柱炎寒湿瘀阻证60例临床观察
- Author:
Xue-Yong YIN
1
Author Information
1. The Second Hospital of Qinhuangdao
- Publication Type:Journal Article
- Keywords:
Ankylosing spondylitis;
BASDAI;
BASFI;
Cold-dampness and blood-stasis syndrome;
Imrecoxib Tablets;
Yaotongning Capsules
- From:
Chinese Traditional and Herbal Drugs
2020;51(21):5426-5430
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To observe the effect of Yaotongning Capsules combined with Imrecoxib Tablets in the treatment of ankylosing spondylitis with cold-dampness and blood-stasis syndrome. Methods: A total of 120 cases with ankylosing spondylitis were randomly divided into two groups: treatment group and control group, with 60 patients in each group. The control group was given Imrecoxib Tablets, and the treatment group was given Imrecoxib Tablets and Yaotongning Capsules. The levels of ESR, CRP, and the scores of BASDAI, BASFI, TCM syndrome were compared before and after treatment, the treatment effect of two groups were evaluated. Results: There was no significant difference in the levels of ESR, CRP and the scores of BASDAI, BASFI, TCM syndrome between two groups before treatment. After treatment, the levels of ESR, CRP and the scores of BASDAI, BASFI, TCM syndrome of the two groups were decreased (P < 0.05), and all the indexes in treatment group were lower than those in control group (P < 0.05), the total effective rate in treatment group (86.67%) was better than that in control group (65.00%) (P < 0.01). Conclusion: Yaotongning Capsules can effectively improve TCM syndrome and functional activity indexes, reduce inflammatory indexes and disease activity, has definite clinical effect on ankylosing spondylitis.
