Research progress on biosynthesis of gastrodin
10.7501/j.issn.0253-2670.2020.22.027
- VernacularTitle: 天麻素生物合成的研究进展
- Author:
De-Hong XU
1
Author Information
1. Laboratory of Biological Engineering, College of Pharmacy, Hunan University of Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Biosynthesis;
Gastrodin;
Microbial transformation;
Plant transformation;
Transformation of engineering microorganisms;
Transformation of wild microorganisms
- From:
Chinese Traditional and Herbal Drugs
2020;51(22):5877-5883
- CountryChina
- Language:Chinese
-
Abstract:
Gastrodin is a major active ingredient in Gastrodia elata, which is one of the traditional rare medicinal herbs in China. It has lots of pharmacological activities, such as reducing blood pressure, anti-epileptic, anti-tumor, and protecting nerve, etc. With the increasing demand for gastrodin in the market and the inherent problems of traditional methods on obtaining gastrodin, new methods are urgently needed to solve various difficulties in the actual production of gastrodin. Biosynthesis is a new method instead of the traditional acquisition method, and has made great progress and achievements in gastrodin acquisition. Therefore, it is necessary to systematically review the biosynthesis of gastrodin from three aspects of biosynthetic pathway, plant transformation and microbial transformation in this paper, hoping to provide valuable reference for further improvement and perfection of gastrodin production method in the future to meet public increasing demand for gastrodin.
