Research progress on Ganoderma lucidum polysaccharide in prevention and treatment of central nervous system diseases
10.7501/j.issn.0253-2670.2020.24.030
- VernacularTitle: 灵芝多糖防治中枢神经系统疾病的研究进展
- Author:
Yu-Huan XIAO
1
Author Information
1. School of Medicine, Yunnan University
- Publication Type:Journal Article
- Keywords:
Alzheimer's disease;
Anti-epileptic effects;
Central nervous system;
Ganoderma lucidum;
Ganoderma lucidum polysaccharide;
Neuroprotection
- From:
Chinese Traditional and Herbal Drugs
2020;51(24):6391-6395
- CountryChina
- Language:Chinese
-
Abstract:
Ganoderma lucidum is a traditional folk common rare medicinal herb, which plays an important role in maintaining human health. Among them, G. lucidum polysaccharide is one of the main bioactive components of G. lucidum, which has various pharmacological effects such as anti-cancer, immunomodulatory, antibacterial, antioxidant, and scavenging free radicals. Due to the complex etiology and pathogenesis of central nervous system diseases, the clinical manifestations are diverse, and the individual response to treatment varies widely, which brings great challenges to clinical treatment. The characteristics and mechanism of the central neuroprotective effect of G. lucidum polysaccharide are reviewed in this paper from the aspects of Alzheimer's disease, anti-epileptic, modulating microglia inflammatory response, etc., in order to provide relevant evidence for its clinical application.
