Determination of isosorbide 5-mononitrate in biological specimen by chromatography: Research advances
- Author:
Jin-Fu JIANG
1
Author Information
1. School of Life Science and Engineering
- Publication Type:Journal Article
- Keywords:
Biological specimen, determination;
Chromatography;
Isosorbide 5-mononitrate;
Sensitivity;
Specificity
- From:
Journal of International Pharmaceutical Research
2010;37(3):213-216
- CountryChina
- Language:Chinese
-
Abstract:
It is difficult to est isosorbide 5-mononitrate in biological specimen due to its unsignificant UV absorption and thermal instability. Therefore, uarious methods such as HPLC, GC-ECD, GC-MS and HPLC-MS/MS were established to meet the needs of assay sensitivity and specificity. Research progress in the chromatography is reviewed in this paper.
