Anti-AIDS drugs targeting drug delivery systems: Research advances
- Author:
Xiang-Yang XIE
1
Author Information
1. Department of Pharmacy
- Publication Type:Journal Article
- Keywords:
Anti-AIDS drugs;
Drug delivery systems;
Drug targeting;
Human immunodeficiency virus
- From:
Journal of International Pharmaceutical Research
2011;38(1):38-41
- CountryChina
- Language:Chinese
-
Abstract:
The discovery and utilization of anti-AIDS drugs therapy have not only increased lifespan, but also enhanced the quality of life of HIV infected people. However, limitations of currently available drug regimens and dosage forms often fail to effectively reduce the HIV viral load in the viral reservoirs in vivo. To overcome the drawbacks of present anti-AIDS drugs' dosage forms, engineered nanocarriers including polymeric nanoparticles, liposomes, solid lipid nanoparticles and dendrimers are developed to facilitate these drugs targeting to the HIV viral reservoirs. This article reviews recent advances in the field of targeting drug delivery systems for the treatment of AIDS.