Nucleoside analogues against hepatitis B virus: Research advances
- Author:
Gui-Qin ZHANG
1
Author Information
1. College of Pharmaceutical Science, Hebei Medical University
- Publication Type:Journal Article
- Keywords:
Antiviral drugs;
Hepatitis B virus;
Nucleoside analogues
- From:
Journal of International Pharmaceutical Research
2013;40(1):8-13
- CountryChina
- Language:Chinese
-
Abstract:
Hepatitis B virus is a serious hazard to human health, and the research and development of anti-hepatitis B virus drugs have become hot topics in the world. Based on the literature at home and abroad, the recent progress of anti-hepatitis B virus agents is reviewed in this paper, including structure characteristics, antiviral mechanism, in vitro and in vivo activity evaluation, and clinical application. Furthermore, the opportunities and challenges for anti-hepatitis B virus drugs in China are prospected.