Effect of probiotics on non-alcoholic fatty liver disease
10.13220/j.cnki.jipr.2014.05.008
- Author:
Xiao-Min YAO
1
Author Information
1. Department of Pharmacy, Zhejiang Pharmaceutical College
- Publication Type:Journal Article
- Keywords:
Gut microbes;
Non-alcoholic fatty liver disease;
Non-alcoholic steatohepatitis;
Probiotics
- From:
Journal of International Pharmaceutical Research
2014;41(5):548-551
- CountryChina
- Language:Chinese
-
Abstract:
Non-alcoholic fatty liver disease (NAFLD) is a common chronic liver disease. It covers a spectrum of liver diseases that range from hepatic steatosis to steatohepatitis and cirrhosis. The increase in its prevalence is linked to obesity and type 2 diabetes. More evidence shows a relation between overgrowth of gut microbiota with NAFLD and non-alcoholic steatohepatitis (NASH). Recently, many studies indicate that probiotics have very good effcts on improving NAFLD. Probiotics have been seen as a new way of treating NAFLD. But probiotics as treatment of NAFLD still need substantiation through more trials with a larger sample size and with longer-term clinical follow-up. Therefore, the research progress in probiotics treatment on animal experiments and clinical trials in NAFLD is reviewed in order to further understand the role of probiotics treatment, and provide the basis for the treatment of NAFLD.
