Quality control of nasal sprays: Research advances
10.13220/j.cnki.jipr.2015.01.015
- Author:
Ying-Juan SHENG
1
Author Information
1. TEAM Academy of Pharmaceutical Sciences
- Publication Type:Journal Article
- Keywords:
Droplet distribution;
Nasal sprays;
Quality control;
Spray pattern
- From:
Journal of International Pharmaceutical Research
2015;42(1):96-100
- CountryChina
- Language:Chinese
-
Abstract:
It is very important to develop nasal sprays with higher bioavailability and better targeting capability by making further use of advanced technology and new methods according to its characteristics. Intensive research has been searched on nasal sprays quality control methods which have been developed in the last few years. This review discusses the critical quality attributes of nasal sprays and the research progress of the quality control methods. Clarifies the characters examine of the nasal spray (pH, osmolality, particle size distribution and viscosity), content and related substances, packaging materials compatibility studies, spray pattern and droplet distribution methods of quality control.
