Advances of circular dichroism application in determination of absolute configuration of flavonolignans
10.13220/j.cnki.jipr.2015.06.014
- Author:
Ning-Bo QIN
1
Author Information
1. School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University
- Publication Type:Journal Article
- Keywords:
Absolute configuration;
Circular dichroism (CD);
Flavonolignan
- From:
Journal of International Pharmaceutical Research
2015;42(6):794-801
- CountryChina
- Language:Chinese
-
Abstract:
Flavonolignans, as a special class of flavonoid, have attracted people's attention for their remarkable hepatopro-tection and anti-cancer activity. However, separation of flavonolignans and identification of their absolute configuration have met with great challenges due to the complexity and similarity of structures. The circular dichroism (CD) rules and their application in analyzing the absolute configuration of flavonolignans are summarized in the review and hopefully it may be helpful for the structure elucidation of flavonolignans.
