Absolute determination of stereochemical configuration of some marine natural products
10.13220/j.cnki.jipr.2015.06.013
- Author:
Yue-Hu PEI
1
Author Information
1. School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University
- Publication Type:Journal Article
- Keywords:
Absoute stereotructure asignment;
Ceramide compounds;
Circular dichroism spectrum;
α β-unsaturated ketones
- From:
Journal of International Pharmaceutical Research
2015;42(6):786-793
- CountryChina
- Language:Chinese
-
Abstract:
The determination of stereochemical absolute structure is an important issue in structural elucidation of natural products. The absolute configuration of natural compounds with a chiral α, β -unsaturated ketone chromorphore can be determined by the Cotton effect in 320-350 nm (n→π,* transition) and 220-260 nm (π→π,* transition) regions of the circular dichroism (CD) spectrum. This paper reviews the absolute stereochemical asignment of some α, β-unsaturated ketone compounds as well as some of the longer fatty chain derived compounds.
