Population pharmacokinetics in children: Research advances
10.13220/j.cnki.jipr.2016.03.008
- Author:
Tao KE
1
Author Information
1. College of Pharmacy, Guangdong Medical College
- Publication Type:Journal Article
- Keywords:
Children;
Individual drug administration;
Nonlinear mixed effect model;
Population pharmacokinetics
- From:
Journal of International Pharmaceutical Research
2016;43(3):445-449
- CountryChina
- Language:Chinese
-
Abstract:
Children are a special group in clinical medical treatment. The significant individual differences require individualized administration of drugs. In recent years, the rapid development of population pharmacokinetics which are widely used in pharmaceutical research is an effective method to achieve individual administration. At home and abroad a large number of population pharmacokinetics are researched in chidren for drugs with narrow therapeutic window or in children with significant individual differences, which can provide information for the individualized dosing of drugs.
