Brain targeted nano-drug delivery systems: Research advances
10.13220/j.cnki.jipr.2016.05.015
- Author:
Zhe-Ming ZHANG
1
Author Information
1. Department of Pharmaceutics, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College
- Publication Type:Journal Article
- Keywords:
Brain targeted;
Nano-drug delivery system;
Targeted drug delivery system
- From:
Journal of International Pharmaceutical Research
2016;43(5):887-892
- CountryChina
- Language:Chinese
-
Abstract:
Central nervous system (CNS) diseases are serious threats to human health. Blood-brain barrier (BBB) plays an important role in protecting the CNS. However, it also impedes the delivery of drugs to CNS and affects the treatment of CNS diseases. Brain targeted nano-drug delivery systems provide the possibility to brain-targeting drug delivery. In this article, we introduce the physiological structure and functions of BBB, and the brain targeting mechanism and the applications of brain-targeting nano-vectors to give a brief overview of the research status of brain targeting nano-drug delivery system.
