C-ANCA-positive glomerulonephritis associated with subacute infective endocarditis caused by Bartonella infection.
10.12701/yujm.2017.34.1.140
- Author:
Min Jeong KIM
1
;
Ha Nee JANG
;
Tae Won LEE
;
Hyun Seop CHO
;
Se Ho CHANG
;
Hyun Jung KIM
Author Information
1. Department of Internal Medicine, Gyeongsang National University School of Medicine, Jinju, Korea. kimhjyh@naver.com
- Publication Type:Case Report
- Keywords:
ANCA-associated glomerulonephritis;
Bartonella;
Infectious endocarditis
- MeSH:
Aged;
Anorexia;
Aortic Valve;
Azotemia;
Bartonella Infections*;
Bartonella*;
Cytoplasm;
Diagnosis;
Doxycycline;
Echocardiography;
Endocarditis*;
Glomerulonephritis*;
Humans;
Korea;
Proteinuria;
Rifampin;
Weight Loss
- From:Yeungnam University Journal of Medicine
2017;34(1):140-145
- CountryRepublic of Korea
- Language:English
-
Abstract:
Glomerulonephritis (GN) is sometimes associated with infective endocarditis (IE). Bartonella endocarditis is difficult to diagnose because it is rare and cannot be detected by blood culture. This is the first report of cytoplasmic anti-neutrophil cytoplasmic antibody-positive subacute endocarditis-associated GN caused by Bartonella infection in South Korea. A 67-year-old man was hospitalized due to azotemia. He complained of weight loss and anorexia for 6 months. A diagnosis of IE was made based upon echocardiographic detection of vegetations on the mitral and aortic valves and a Bartonella antibody titer of 1:2,048. Renal histology identified focal crescentic GN. Azotemia and proteinuria improved after doxycycline and rifampin treatment combining with steroid therapy.
