Aptamers specific for biotoxins: research advances
10.13220/j.cnki.jipr.2020.09.004
- VernacularTitle: 生物毒素适配体的研究进展
- Author:
Min ZHANG
1
Author Information
1. Institute of Pharmacology and Toxicology, Academy of Military Medical Sciences, Academy of Military Sciences
- Publication Type:Journal Article
- Keywords:
Application;
Aptamers;
Biotoxins
- From:
Journal of International Pharmaceutical Research
2020;47(9):703-708
- CountryChina
- Language:Chinese
-
Abstract:
Biotoxins widely exist in foods and environments, posing a serious threat to human health. Specific and sensitive detection of biotoxins is the most effective way to prevent unexpected problems caused by biotoxins. In recent years, aptamer-based bio-toxin detections have gradually been prevailing. Aptamers, a new type of recognition molecules with high affinity and specificity, have been used to produce a variety of biosensors. In addition, some aptamers can neutralize the toxicity of biotoxins and inhibit their activities, with the effect to replace the antibody to some extent. This article briefly describes the research advances on biotoxin aptamers and prospects the development and application of aptamers targeting biotoxins in the future.
