Significance of carbohydrate antigen 50 expression in colorectal carcinoma
- Author:
Zhen-Hua MA
1
Author Information
1. Department of General Surgery
- Publication Type:Journal Article
- Keywords:
Carbohydrate antigen 50;
Colorectal carcinoma;
Immunohistochemistry
- From:Academic Journal of Xi'an Jiaotong University
2009;21(4):249-251
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To evaluate the significance of carbohydrate antigen 50 (CA50) expression in colorectal carcinoma. Methods: Immunohistochemical staining was used to detect CA50 expression in 10 cases of normal colorectal mucosa and 40 cases of cancer mucosa. Results: The expression of CA50 increased in normal colorectal mucosa, cancer distant mucosa, cancer adjacent mucosa and cancer mucosa, and there were significant differences among them (P < 0.05). The expression of CA50 in colorectal carcinoma was correlated with the degree of differentiation, Duke's stage and lymphatic metastases (P<0.05). Conclusion: The expression of CA50 can be used as a valuable index in evaluating the biological characteristics and prognosis of colorectal carcinoma.
