Apoptosis of lumbar spinal cord neurons in cauda equina syndrome rats
- Author:
Si-Yue XU
1
Author Information
1. Second Orthopedic Department
- Publication Type:Journal Article
- Keywords:
Apoptosis;
Cauda equina syndrome;
Lumbar spine
- From:Academic Journal of Xi'an Jiaotong University
2010;22(2):120-122
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore the law of apoptosis of lumbar spinal cord neurons in cauda equina syndrome (CES). Methods: Cauda equina of rats was compressed by a piece of silica gel stick. From day 1 to day 28, the lumbar spinal cord specimens were harvested and assessed by Nissl's staining and TUNEL staining. Results: Compression of cauda equina caused lesion and apoptosis of neurons in lumbar spinal cord, and the extent of apoptosis reached the peak on 7th day after compression. Conclusion: Apoptosis of neurons in lumbar spinal cord might be one of the reasons why patients with CES get poor prognosis.
