Role of microRNAs in liver regeneration
10.16098/j.issn.0529-1356.2017.02.020
- Author:
Xia-Yan ZANG
1
Author Information
1. State Key Laboratory Cultivation Base for Cell Differentiation Regulation, College of Life Science, He'nan Normal University
- Publication Type:Journal Article
- Keywords:
Hepatocyte proliferation;
Liver regeneration;
MicroRNAs
- From:
Acta Anatomica Sinica
2017;48(2):230-235
- CountryChina
- Language:Chinese
-
Abstract:
MicroRNAs (miRNAs) are a group of endogenous, small, noncoding RNA molecules which can regulate gene expression at posttranscriptional level by binding to the 3 ' untranslated regions (3' UTRs) of their target mRNAs. It has been reported that miRNAs regulated a variety of biological processes, including cell proliferation, differentiation, apoptosis, metabolic process, organ development, etc. Liver as one of the organs with extraordinary regenerative abilities, is considered to be an important material for the research of regeneration mechanism. This paper summarized the research advance of the role of microRNAs in liver regeneration.
