Research progress of janus kinase - Signal transducers and activators of transcription signal transduction pathway and neurogenesis
10.16098/j.issn.0529-1356.2019.05.024
- Author:
Kuang-Pin LIU
1
Author Information
1. Institute of Neuroscience, Kunming Medical University
- Publication Type:Journal Article
- Keywords:
Janus kinase;
Neurogenesis;
Signal transducers and activators of transcription
- From:
Acta Anatomica Sinica
2019;50(5):684-689
- CountryChina
- Language:Chinese
-
Abstract:
Janus kinase-signal transducers and activators of transcription (JAK-STAT) signal transduction pathway is related to cellular biological activities and occurrence and development of many diseases. In recent years, JAK-STAT signal transduction pathway has been found in the central nervous system to regulate neurodegenerative diseases and nerve regeneration after nerve injury: however, promoting endogenous neurogenesis as a new direction of nerve regeneration research is also closely related to the positive or negative regulation of JAK-STAT signal transduction pathway. This article reviews the research progress of JAK-STAT signal transduction pathway, neurogenesis, and JAK-STAT signal transduction pathway regulating neurogenesis.
