Histone modification and glioma tumorigenesis
10.3969/j.issn.1674-8115.2018.01.001
- Author:
Hai-Zhong FENG
1
Author Information
1. Renji-Med X Clinical Stem Cell Research Center, Renji Hospital, Shanghai Jiao Tong University School of Medicine
- Publication Type:Journal Article
- Keywords:
Acetylation;
Glioma;
Histone modification
- From:
Journal of Shanghai Jiaotong University(Medical Science)
2018;38(1):1-3
- CountryChina
- Language:Chinese
-
Abstract:
Although epigenetic regulation of histone modification has attracted more and more attention, the underlying mechanisms are still unclear. The present review introduces the role of acetylated H3 lysine 23 (H3K23ac) in glioma tumorigenesis, and demonstrates a new mechanism by which H3K23ac regulates gliomagenesis, which may provide novel approaches to glioma treatment.