Relationship between the APOE genotypes and the common major psychosis
10.3969/j.issn.1674-8115.2018.06.022
- Author:
Xiao-Yan YU
1
Author Information
1. Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine
- Publication Type:Journal Article
- Keywords:
Alzheimer's disease;
Apolipoprotein E;
Genotype;
Major psychosis
- From:
Journal of Shanghai Jiaotong University(Medical Science)
2018;38(6):704-707
- CountryChina
- Language:Chinese
-
Abstract:
Apolipoprotein E (APOE) is a lipid transfer protein, which plays an important role in maintaining the stabilization of nerve and recovering. Alzheimer's disease (AD) is a neurodegenerative disorder. Most studies showed that APOE genotypes were closely related with AD. In clinical practice, AD is mainly manifested as progressive cognitive decline, and often accompanied by mental behavioral symptoms. These symptoms also exist in common severe mental illness. It is worth thinking about the correlation between APOE genotypes and these diseases. This article reviewed the relationship between the APOE genotypes and the common major psychosis.
