Antimicrobial Activity of Medizyme-Plus, Developed for Cleansing Prior to Disinfection/Sterilization.
- Author:
Hae In BANG
1
;
Tae Youn CHOI
Author Information
1. Department of Laboratory Medicine, Soonchunhyang University Seoul Hospital, Seoul, Korea. choity@schmc.ac.kr
- Publication Type:Original Article
- Keywords:
Disinfectants;
Ammonium compounds;
Protease
- MeSH:
Agar;
Ammonium Compounds;
Amylases;
Bacteria;
Cross Infection;
Disinfectants;
Glucose;
Gyeonggi-do;
Hygiene;
In Vitro Techniques;
Public Health;
Yeasts
- From:Soonchunhyang Medical Science
2016;22(2):112-114
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: Disinfectants are essential for public health and environmental hygiene. The aim of this study was to investigate the in vitro antimicrobial activity of Medizyme-Plus (Soosan Co. Ltd., Seongnam, Korea) developed for cleansing prior to disinfection/ster-ilization, against bacteria and yeasts. METHODS: Clinical isolates were exposed to Medizyme-Plus (a product containing quaternary ammonium and a protease, amylase, and lipase) for various periods (0.5, 1, 2, 5, 10, 15, and 30 minutes). After exposure, the mixtures of isolates and Medizyme-Plus were inoculated into tryptic soy broths. To enumerate the surviving bacteria or yeasts, treated isolates were inoculated onto solid agar media (blood agar, MacConkey agar, and Sabouraud dextrose agar) and cultured at 35℃. RESULTS: All strains of bacteria and yeasts showed a 5-log10 reduction within 0.5 minutes of exposure to Medizyme-Plus. CONCLUSION: Medizyme-Plus can be used as a low-level disinfectant, in addition to cleanser, for hospital infection control. It will be necessary to perform disinfection/sterilization after cleansing with Medizyme-Plus.
