Effect of imblanced vaginal flora on female infertility
10.3969/j.issn.1674-8115.2018.08.022
- Author:
Wei-Wei CHU
1
Author Information
1. Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Renji Hospital, Shanghai Jiao Tong University School of Medicine
- Publication Type:Journal Article
- Keywords:
Bacterial vaginosis;
Female infertility;
Inflammation;
Vaginal microbiota
- From:
Journal of Shanghai Jiaotong University(Medical Science)
2018;38(8):990-995
- CountryChina
- Language:Chinese
-
Abstract:
Recently the incidence of female infertility is on the rise. The variable and complicated cause of infertility makes it difficult to diagnose in clinical practise. The relationship between vaginal flora and host immune system plays a vital role in female physiological function. Vaginal microbiota dysbiosis may be related to all kinds of infertility, such as tube infertility, endometriosis, anovulatory infertility and idiopathic infertility. In other words, vaginal microbiota dysbiosis may take part in the infertile process. For now the mechanism is far from clear. Some scientists suppose that Lactobacillus deficiency, chronic inflamation and low estrogen level might get involved in this pathophysiological progression, which needs to be studied in the furture.