Research progress of endogenous exosomes as nano drug delivery system for treatment of myocardial ischemia
10.3969/j.issn.1674-8115.2018.08.021
- Author:
Ting HONG
1
Author Information
1. Department of Anesthesiology and SICU, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
- Publication Type:Journal Article
- Keywords:
Exosome;
Myocardial ischemia;
Nano-drug delivery system;
Treatment
- From:
Journal of Shanghai Jiaotong University(Medical Science)
2018;38(8):984-989
- CountryChina
- Language:Chinese
-
Abstract:
Exosomes are natural nano vesicles secreted by living cells, which play an important role in cellular communication and substance transportation. As a kind of carrier of human endogenous for drug transportation, many advantages of exosomes are in sight, for example, low toxicity, non immunogenicity, good permeability and high-targeting. In recent years, small molecular chemical drugs, nucleic acids and proteins have been successfully delivered by exosomes. This novel carrier is expected to provide strong support for the clinical treatment of myocardial ischemia. The research progress of exosomes as a kind of carrier in the treatment of myocardial ischemia was briefly summarized in this article.
