Meigs' Syndrome with Elevated Cancer Antigen 125.
- Author:
Hye Na PARK
1
;
Sun Gyoeng KIM
;
Yun Sook KIM
Author Information
1. Department of Obstetrics and Gynecology, Soonchunhyang University Cheonan Hospital, Soonchunhyang University College of Medicine, Cheonan, Korea. drsook@schmc.ac.kr
- Publication Type:Case Report
- Keywords:
Meigs' syndrome;
Fibroma;
Ascites;
CA-125 antigen
- MeSH:
Abdomen;
Aged;
Ascites;
CA-125 Antigen;
Diagnosis, Differential;
Female;
Fibroma;
Humans;
Hysterectomy;
Laparotomy;
Meigs Syndrome*;
Ovary;
Pleural Effusion;
Thorax
- From:Soonchunhyang Medical Science
2016;22(2):129-131
- CountryRepublic of Korea
- Language:English
-
Abstract:
Meigs' syndrome is a fibroma associated with ascites and/or pleural effusion and several cases have been reported in association with elevated serum cancer antigen (CA) 125 level. We report here on a 72-year-old woman who presented with palpable huge pelvic mass. Abdomen and pelvic computed tomography showed a heterogenous huge pelvic mass measuring 210×110 mm with large amount of ascites. No pleural effusion was detected on chest X-ray. CA 125 level was 327 IU/mL. The patient underwent laparotomy during which a mass measuring 210×110 mm was detected in her right ovary with 1,000 mL of ascites. Histology showed ovarian fibroma. We performed total abdominal hysterectomy with bilateral salpingo-oophorectomy. Postmenopausal woman with ovarian tumor, ascites, and elevated CA 125 may indicate malignant ovarian tumor, but Meigs' syndrome must be considered as differential diagnosis.