Hypopituitarism Presenting as Osteoporotic Fracture after Cured Tuberculous Meningitis.
- Author:
Jung Yeop LEE
1
;
Mi Jung KIM
;
Min A KIM
;
Se Hyuk KWON
;
Eun Kyoung KIM
;
Kyung Ae LEE
Author Information
1. Division of Endocrinology and Metabolism, Department of Internal Medicine, Chonbuk National University Hospital, Chonbuk National University Medical School, Jeonju, Korea. kaleey@hanmail.net
- Publication Type:Case Report
- Keywords:
Tuberculosis, meningeal;
Hypopituitarism;
Vitamin D deficiency
- MeSH:
Body Composition;
Hypopituitarism*;
Incidence;
Osteoporotic Fractures*;
Pituitary Hormones;
Pituitary Hormones, Anterior;
Sexual Development;
Tuberculosis, Meningeal*;
Vitamin D;
Vitamin D Deficiency
- From:Soonchunhyang Medical Science
2016;22(2):141-143
- CountryRepublic of Korea
- Language:English
-
Abstract:
Tuberculous meningitis is a well-known cause of hypothalamic pituitary dysfunction. However, deficiencies of anterior pituitary hormones may only become evident years after recovery because symptoms are of insidious-onset and nonspecific. Pituitary hormones are essential for normal growth and sexual development in childhood, and for maintenance of healthy body composition. In addition, pituitary hormones and vitamin D are important for cardiovascular and bone health. Although evidence of the relationship between hypovitaminosis D and hypopituitarism is limited, some studies suggested that the incidence of vitamin D deficiency increased in hypopituitarism. We describe herein an unusual case of hypopituitarism and severe hypovitaminosis D presenting as osteoporotic fracture after cured tuberculous meningitis.
