Minimal Change Nephrotic Syndrome Developed after Thymectomy in a Patient with Thymoma.
- Author:
Fa Mee DOH
1
;
Seon Jung JANG
;
Hyang Mo KOO
;
Eun Jin KIM
;
Hye Sun SHIN
;
Seung Hyeok HAN
;
Shin Wook KANG
;
Kyu Hun CHOI
;
Tae Hyun YOO
Author Information
1. Department of Internal Medicine, Yonsei University College of Medicine, Korea. yoosy0316@yuhs.ac
- Publication Type:Case Report
- Keywords:
Thymoma;
Thymectomy;
Minimal change disease
- MeSH:
Administration, Oral;
Adult;
Biopsy;
Humans;
Methylprednisolone;
Myasthenia Gravis;
Nephrosis, Lipoid;
Nephrotic Syndrome;
Pleura;
Prednisolone;
Pyridostigmine Bromide;
Recurrence;
Thymectomy;
Thymoma
- From:Korean Journal of Nephrology
2011;30(4):404-408
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report a case of patient with malignant thymoma, who developed nephrotic syndrome several years after thymectomy. This 38-year-old man was diagnosed as myasthenia gravis and malignant thymoma and underwent thymectomy in 2004. Tumor resection and systemic chemotherapy were performed after recurrence in pleura in 2006. He also took pyridostigmine to control his symptoms of myasthenia gravis after thymectomy. Four years later, even though there was no evidence of recurrence of thymoma, he developed a nephrotic syndrome and was diagnosed as a minimal change disease on renal biopsy. After pulse therapy with methylprednisolone followed by oral administration of prednisolone therapy, nephrotic syndrome was improved.
