Value of prostate anterior horn biopsy in the diagnosis of prostate cancer
10.3969/j.issn.1674-8115.2019.05.014
- Author:
Shao-Wei XIE
1
Author Information
1. Department of Ultrasound, Renji Hospital, Shanghai Jiao Tong University School of Medicine
- Publication Type:Journal Article
- Keywords:
Anterior horn;
Biopsy;
Prostate cancer
- From:
Journal of Shanghai Jiaotong University(Medical Science)
2019;39(5):518-521
- CountryChina
- Language:Chinese
-
Abstract:
Objective • To evaluate population anterior horn biopsy in the diagnosis of prostate cancer. Methods • The clinical and pathological data of 1 679 patients who underwent ultrasound-guided initial 12-core prostate biopsies at Renji Hospital, Shanghai Jiao Tong University School of Medicine, were retrospectively analyzed. The performances of 12-core (including anterior horn) biopsy and the 10-core (except anterior horn) biopsy were compared in total population and different subgroups for the detection rates of prostate cancer. Results • Of the 1 679 patients, 678 (40.4%) were diagnosed with prostate cancer, and 59 (8.7%) were only positive at anterior horns. After excluding the anterior horn biopsy, the detection rate was 36.9% (619/1 679), which was lower than the overall detection rate including the anterior horn biopsy (40.4% vs 36.9%, P=0.046). In prostate specific antigen (PSA) and prostate volume subgroups, for the patients with PSA>10 ng/mL and prostate volume ≥ 30 mL, the biopsy detection rate was improved by adding the anterior horn biopsy (P<0.05). The patients with only positive anterior horn biopsy had higher prostate volumes and lower Gleason scores, compared with the patients with positive biopasy excluding anterior horn (P=0.006, P=0.000). Conclusion • Adding the anterior horn biopsy could improve the prostate cancer detection rate, recommended to be routinely used in the initial prostate biopsies.
