Atmospheric fine particulate matter causing Alzheimer's disease through olfactory bulb pathway: a review of recent studies
10.3969/j.issn.1674-8115.2019.06.017
- Author:
Hao WANG
1
Author Information
1. Shanghai Jiao Tong University School of Publish Health
- Publication Type:Journal Article
- Keywords:
Alzheimer’s disease (AD);
Fine particulate matter (PM2.5);
Neuroinflammation;
Olfactory bulb;
Oxidative stress
- From:
Journal of Shanghai Jiaotong University(Medical Science)
2019;39(6):666-670
- CountryChina
- Language:Chinese
-
Abstract:
With the improvement of quality of life, the life expectancy of residents is generally prolonged, and people suffering from Alzheimer’s disease (AD) is increasing. Epidemiological and animal experiments have found that atmospheric particulate matter is associated with AD. This article briefly reviews the mechanisms of AD-related oxidative stress damage and neuroinflammation caused by atmospheric fine particulate matter entering the brain via olfactory bulb pathway.