Advances in research on relationship between osteoporosis and intestinal microbe
10.3969/j.issn.1674-8115.2019.10.020
- Author:
Zi-Lin LI
1
Author Information
1. Shanghai Jiao Tong University School of Public Health
- Publication Type:Journal Article
- Keywords:
Bone turnover;
Intestinal microbe;
Osteoporosis
- From:
Journal of Shanghai Jiaotong University(Medical Science)
2019;39(10):1214-1217
- CountryChina
- Language:Chinese
-
Abstract:
Osteoporosis, one of the severest diseases in the middle-aged and elderly population, is the result of the disorder of the normal bone turnover process. At present, many studies have shown that bone turnover is closely related to the microbial environment in the human body. The largest microbiota in the human body exists in the intestine and plays an important role in the normal physiological activities of the body, such as nutrition, metabolism, immunity and barrier. Intestinal microbe can regulate endocrine and immune system through a series of processes, thereby affecting the process of bone turnover in the body. This article briefly reviews the current research about the effects of intestinal microbe on the process of bone turnover in the body. It is expected to provide new ideas for the treatment of osteoporosis by exploring the relationship between osteoporosis and intestinal microbe.