Incidence and risk factors of infection related to totally implantable access port in upper arm in cancer patients
10.3969/j.issn.1674-8115.2019.10.014
- Author:
Xiao-Xia QIU
1
Author Information
1. Department of Oncology, Renji Hospital, Shanghai Jiao Tong University School of Medicine
- Publication Type:Journal Article
- Keywords:
Implantable access port;
Infection;
Tumor patient;
Upper arm
- From:
Journal of Shanghai Jiaotong University(Medical Science)
2019;39(10):1183-1187
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore the incidence and risk factors of infection related to totally implantable access port (TIAP) in upper arm in cancer patients. Methods: A total of 1 961 patients who received TIAP for deliverance of chemotherapy at Renji Hospital, Shanghai Jiao Tong University School of Medicine during the period from February 2014 to December 2018. The general clinical data, catheterization status, bacteriological data and incidence of TIAP-related infections were retrospectively analyzed. The univariate analysis and multivariate Logistic regression analysis were used to determine the risk factors TIAP-related infections. Results: A total of 43 patients developed TIAP-related infections, with an incidence of 2.2% (43/1 961). The mean time interval from the implantation of upper arm TIAP to the diagnosis of infection was (116.88±95.39) d (7-377 d). In univariate analysis, gender (P=0.001), catheter diameter (P=0.000), upper extremity venous thrombosis (UEVT) (P=0.000) and outpatient (P=0.005) were significantly associated with the risk of infection related to upper arm TIAP. Multivariate binary Logistic regression analysis showed that gender (OR=0.35, P=0.012), UEVT (OR=31.59, P=0.000) and catheter diameter (OR=2.81, P=0.005) were three significant independent predictors of infection related to upper arm TIAP. Conclusion: Gender, UEVT and catheter diameter are independent risk factors for upper arm TIAP-related infection.