Advances in the study of T cell immunity in invasive fungal infections secondary to sepsis
10.3969/j.issn.1674-8115.2019.11.018
- Author:
Yi-Si ZHAO
1
Author Information
1. Department of Critical Care Medicine, The First Affiliated Hospital of Chongqing Medical University
- Publication Type:Journal Article
- Keywords:
Immunotherapy;
Invasive fungal infections;
Sepsis;
T-cell subsets
- From:
Journal of Shanghai Jiaotong University(Medical Science)
2019;39(11):1325-1328
- CountryChina
- Language:Chinese
-
Abstract:
Invasive fungal infections (IFI) has high morbidity and mortality. It is more common in hospital infections, and especially in sepsis, the risk of secondary IFI is increased. Immunosuppression of sepsis may affect immune function of T cells, and various T cells subsets have different effects on various fungal pathogens of IFI. The review discusses the pathophysiological processes, mechanism and therapeutic methods of T cell immunity in IFI secondary to sepsis, in order to summarize the role of T cells in IFI secondary to sepsis and introduce the new immunotherapy.
