Clinicopathlogic characteristics of multiple synchronous early gastric cancers.
- Author:
Hoi Jin KIM
1
;
Jun Haeng LEE
;
June Sang LEE
;
Tae Gun MOON
;
Jae J KIM
;
Jong Chul RHEE
;
Jae Hyung NOH
;
Tae Sung SOHN
;
Sung KIM
Author Information
1. Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. leejh@smc.samsung.co.kr
- Publication Type:Original Article
- Keywords:
Early gastric cancer;
Multiple early gastric cancers;
Synchronous gastric cancer
- MeSH:
Gastrectomy;
Humans;
Lymph Nodes;
Male;
Medical Records;
Neoplasm Metastasis;
Recurrence;
Retrospective Studies;
Stomach;
Stomach Neoplasms*
- From:Korean Journal of Medicine
2007;72(4):360-367
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: With the progress of limited surgery and endoscopic treatment for early gastric cancer (EGC), multiple synchronous EGCs, a cause of recurrence, become more important. The objective of this study was to elucidate the characteristics of multiple synchronous EGCs with an emphasis on features of preoperatively undiagnosed lesions. METHODS: We retrospectively reviewed medical records of 496 patients who underwent a gastrectomy for EGC at our institution between January 2004 and December 2004. RESULTS: Twenty-four patients (4.8%) had multiple synchronous EGCs with 24 main and 27 accessory lesions. Multiple synchronous EGCs showed male predominance (p=0.03). Other characteristics including lymph node metastasis were the same as with single EGC. Out of 27 accessory lesions, six lesions (22%) were not detected preoperatively in six patients (25%). Macroscopically five lesions were flat and one lesion was depressed. Five lesions were located at the anterior or posterior wall of the middle and low third portion and one lesion was located at the lesser curvature side of the upper third portion of the stomach. Two lesions were 4 mm, one lesion was 8 mm, two lesions were 12 mm and one lesion was 15 mm in size (mean diameter = 9.1 mm). Histologically, four lesions were of the differentiated type and two lesions were of the undifferentiated type. CONCLUSIONS: Multiple synchronous EGCs have same clinicopathologic features as a single EGC except for male predominance. Considering the possibility of a synchronous lesion, one should examine the entire stomach precisely with special attention to the anterior, posterior wall and lesser curvature side of the same or neighboring area of a known EGC lesion before treatment.
