Value of transformation zone type in the evaluation of random biopsy among patients without visible lesions under colposcopy
10.3969/j.issn.1674-8115.2020.09.008
- VernacularTitle: 转化区类型在评估阴道镜下未见宫颈病变者随机活检中的价值
- Author:
Wei CANG
1
Author Information
1. Shanghai Key Laboratory of Gynecology Oncology, Department of Obstetrics and Gynecology, Renji Hospital
- Publication Type:Journal Article
- Keywords:
Cervical high-grade squamous intraepithelial lesion;
Cervical transformation zone;
Colposcopy;
Random biopsy
- From:
Journal of Shanghai Jiaotong University(Medical Science)
2020;40(9):1213-1217
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore the value of cervical transformation zone (TZ) type in assessing whether a random biopsy should be used to diagnose high-grade squamous intraepithelial lesion (HSIL) among patients without visible lesions under colposcopy. Methods: A total of 517 patients who underwent colposcopy (without visible lesions) due to high risk subtype infection of human papillomavirus (HPV) or thinprep cytologic test (TCT) abnormality were enrolled. TZ types were identified, random biopsies were performed, and the value of TZ type, Ⅱand III in the diagnosis of HSIL was evaluated. Results: There were 517 cases without visible lesions under colposcopy. Three hundred and ninety-six of them were TZ type III, and the detection rate of HSIL was 3.8% (15/396) by random biopsy, while one hundred and twenty one of them were TZ type and Ⅱ, and the detection rate of HSIL was 8.3% (10/121). Compared with the TZ type III, the detection rate of HSIL in the TZ type and Ⅱ was significantly increased (P=0.000). Logistic regression showed that TCT abnormality, TZ type and Ⅱ were the risk factors for HSIL detection in patients without visible lesions under colposcopy. Conclusion: Random multipoint biopsy can significantly increase detection rate of cervical HSIL when no visible lesion is visualized under colposcopy, particularly in women with abnormal TCT results or TZ type and Ⅱ.
